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產(chǎn)品基本信息

產(chǎn)品編號：C982940

產(chǎn)品名稱：O-Des(Cyclopropylmethyl) O-cyclobutyl Roflumilast

產(chǎn)品CAS：

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	C982940
名稱:	O-Des(Cyclopropylmethyl) O-cyclobutyl Roflumilast
別名:	3-Cyclobutoxy-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
分子式:	C??H??Cl?F?N?O?
外觀:	白色至白色固體
熔點:	134 - 136°C
分子量:	403.21
儲存:	-20Â°C Freezer
溶解性:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	O-Des(cyclopropylmethyl) O-cyclobutyl Roflumilast is an intermediate used in the synthesis of Roflumilast (R639700). Roflumilast is a selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease.
參考文獻(xiàn)	Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al.: Lancet, 366, 563 (2005);

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