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N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7

產(chǎn)品基本信息

產(chǎn)品編號：D204052

產(chǎn)品名稱：N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7

產(chǎn)品CAS：

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	D204052
名稱:	N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7
別名:	(αR,βS)-α-Hydroxy-β-[[(2E)-1-oxo-2-hexen-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester-d7; (αR,βS)-α-Hydroxy-β-[[(2E)-1-oxo-2-hexenyl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester-d7; Paclitaxel Impurity Q-d7
參考CAS號:	未標(biāo)記：502626-06-4
分子式:	C??H??D?NO??
分子量:	852.97
種類:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7 is the isotope labelled analog of N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel (D204050); an impurity of Paclitaxel (P132500) which is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
參考文獻(xiàn)	Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984); Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984); Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995); Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002); Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004)

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