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產(chǎn)品基本信息

產(chǎn)品編號(hào)：H491020

產(chǎn)品名稱(chēng)：8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic Acid

產(chǎn)品CAS：74145-11-2

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	H491020
名稱(chēng):	8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic Acid
別名:	5,6,7,8-Tetrahydro-8-hydroxy-1-naphthalenecarboxylic Acid
CAS號(hào):	74145-11-2
分子式:	C??H??O?
外觀:	白色至Off-white
分子量:	192.21
儲(chǔ)存:	Room Temperature
溶解度:	DMF; DMSO;
種類(lèi):	Building Blocks; Miscellaneous;
應(yīng)用:	8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic Acid is an intermediate in the synthesis of N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide (A795305), an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
參考文獻(xiàn)	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004)

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