 ?您的位置：對照品 > 標準物質(zhì) > 一級標準物質(zhì) > |
|
|
|
| 產(chǎn)品基本信息 |
|
| 產(chǎn)品編號：H805180 |
| 產(chǎn)品名稱：(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride |
| 產(chǎn)品CAS： |
| 規(guī)格含量：10mg |
| 產(chǎn)品價格：面議 |
| 聯(lián)系我們: |
 |
|
 |
|
|
| 產(chǎn)品詳細介紹 |
| 標準品編號: |
H805180 |
| 名稱: |
(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride |
| 分子式: |
C??H??ClN?O? |
| 分子量: |
300.78 |
| 種類: |
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 應(yīng)用: |
(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
| 參考文獻 |
|
|
|
|
|
|
