Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Ledipasvir Isomer Impurity B is an isomer of Ledipasvir (L320100), which is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.
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