產(chǎn)品基本信息
產(chǎn)品編號(hào)：S676720
產(chǎn)品名稱：(1R,3S)-Solifenacin Hydrochloride
產(chǎn)品CAS：180468-40-0
規(guī)格含量：25mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
S676720
名稱:
(1R,3S)-Solifenacin Hydrochloride
別名:
(1R)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3S)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride;
CAS號(hào):
180468-40-0
參考CAS號(hào):
774517-20-3 - Free base 1262506-09-1 - Succinate s
分子式:
C??H??ClN?O?
外觀:
白色至淡黃色固體
熔點(diǎn):
>124°C (dec.)
分子量:
398.93
儲(chǔ)存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
類別:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
(1R,3S-)Solifenacin Hydrochloride is an optical isomer of Solifenacin Hydrochloride (S676700), a muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
參考文獻(xiàn)
Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006); Naito, R. et al.: J. Med. Chem., 48, 6597 (2005);
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