N-[(6,7-Difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine; SR 3029
CAS號:
1454585-06-8
分子式:
C??H??F?N?O
分子量:
480.45
類別:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
SR-3029 is a potent and selective CK1δ and CK1ε inhibitor (IC50 values are 44 and 260 nM, respectively). Exhibits selectivity for CK1δ and CK1ε over a panel of other kinases. Inhibits proliferation of melanoma and breast cancer cell lines in vitro. Also inhibits growth of breast tumor xenografts in mice.
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