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產(chǎn)品基本信息

產(chǎn)品編號(hào)：A622640

產(chǎn)品名稱：2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyph

產(chǎn)品CAS：260414-73-1

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	A622640
名稱:	2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Monohydrochloride
別名:	2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Hydrochloride (1:1); T1032 N-Oxide
CAS號(hào):	260414-73-1
分子式:	C??H??ClN?O?
分子量:	620.05
類別:	Standards; Enzyme Activators and Inhibitors;
應(yīng)用:	2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Monohydrochloride, is a selective metabolite that is generated by cytochrome P450 3A5 (CYP3A5) oxidation of A622635.These compounds are also 4-Aryl-1-isoquinolinone Derivatives, which are shown to be novel, potent, and selective Phosphodiesterase 5 (PDE5) Inhibitors.
參考:	Song, X., et al.: Bio. Med. Chem. Lett., 22, 1611(2012); Tatsuzo, U., et al.: J. Med. Chem., 44, 2204 (2001);

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