1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Bis(1-methylethyl) Ester; Nimodipine EP Impurity B
雜質(zhì):
Nimodipine EP Impurity B
CAS號(hào):
21881-78-7
分子式:
C??H??N?O?
外觀:
Pale Beige Solid
熔點(diǎn):
128 - 131°C
分子量:
402.44
儲(chǔ)存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解性:
Chloroform (Slightly), Methanol (Slightly)
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).
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