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產(chǎn)品基本信息

產(chǎn)品編號：H281390

產(chǎn)品名稱：1,2,3,3’,4,4’-Hexahydro-[1,1’-binaphthalene]-8,8’-

產(chǎn)品CAS：

規(guī)格含量：25mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	H281390
名稱:	1,2,3,3’,4,4’-Hexahydro-[1,1’-binaphthalene]-8,8’-dicarboxylic Acid
分子式:	C??H??O?
外觀:	Off-white, 淡黃色固體
分子量:	348.39
儲存:	Room Temperature
溶解度:	Dichloromethane; Methanol; Ethyl Acetate;
種類:	Building Blocks; Miscellaneous;
應用:	1,2,3,3’,4,4’-Hexahydro-[1,1’-binaphthalene]-8,8’-dicarboxylic Acid is an intermediate used in the synthesis of N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide (A795305), which is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
參考文獻	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

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