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產(chǎn)品基本信息
產(chǎn)品編號：L175808
產(chǎn)品名稱：Lapatinib
產(chǎn)品CAS：231277-92-2
規(guī)格含量：250mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
L175808
名稱:
Lapatinib
別名:
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine; 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline; GSK 572016; GW 2016; GW 572016; GW 572016X; N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methanesulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine; N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine; N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine; N-[4-(3-Fluorobenzyloxy)-3-chlorophenyl]-6-[5-[[2-(methylsulfonyl)ethylamino]methyl]furan-2-yl]quinazolin-4-amine; Tycerb; Tykerb; Tyverb;
CAS號:
231277-92-2
分子式:
C??H??ClFN?O?S
外觀:
淡黃色固體
熔點(diǎn):
144-146ºC
分子量:
581.06
儲存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly, Sonicated)
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Lapatinib is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. This drug is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
參考文獻(xiàn)
Konecny, G., et al.: Cancer Res., 66, 1630 (2006); Geyer, C., et al.: N. Engl. J. Med., 355, 2733 (2006);
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