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產(chǎn)品基本信息

產(chǎn)品編號(hào)：P217500

產(chǎn)品名稱(chēng)：PD-166285

產(chǎn)品CAS：212391-63-4

規(guī)格含量：2mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	P217500
名稱(chēng):	PD-166285
別名:	6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one Hydrochloride;
CAS號(hào):	212391-63-4
分子式:	C??H??Cl?N?O?
外觀:	Yellow Solid
熔點(diǎn):	239-242?C
分子量:	585.35
儲(chǔ)存:	Hygroscopic, 冰箱, Under inert atmosphere
溶解度:	DMSO, Methanol
穩(wěn)定性:	Hygroscopic
類(lèi)別:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	A broad-spectrum receptor tyrosine kinase (RTK) inhibitor which shows anti-angiogenic activity and anti-tumor efficacy in combination with photodynamic therapy (PDT).
參考文獻(xiàn)	Star, W., et al.: Cancer Res., 46, 2532 (1986), Sawutz, D., et al.: Biochem. Pharm., 51, 1631 (1996), Voest, E., et al.: Anti-Cancer Drugs, 7, 723 (1996), Connolly, C., et al.: Bioorg. Med. Chem. Lett., 7(18), 2415 (1997), Hamby, J., et al.: J. Med. Chem., 40, 2296(1997),

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