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產(chǎn)品基本信息
產(chǎn)品編號：A632980
產(chǎn)品名稱：3-Aminopiperidine-2,6-dione Hydrochloride
產(chǎn)品CAS：24666-56-6
規(guī)格含量：5g
產(chǎn)品價格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
A632980
名稱:
3-Aminopiperidine-2,6-dione Hydrochloride
別名:
3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Amino-2,6-piperidinedione Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride;ÂDL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride
CAS號:
24666-56-6
備用CAS:
Free Base: 2353-44-8
分子式:
C?H?ClN?O?
外觀:
白色固體
熔點(diǎn):
>208ºC (dec.)
分子量:
164.59
儲存:
冰箱保存
溶解度:
DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
類別:
Building Blocks; Miscellaneous;
應(yīng)用:
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induceÂubiquitination and degradation of CK1α in del(5q) MDS.ÂIt can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.
文獻(xiàn)
Kronke, J., et al.: Nature 523, 183 (2015);ÂLiu C., et al.:ÂFaming Zhuanli Shenqing CNÂ105348257ÂAÂ20160224 (2016);ÂRao, R., et al. :ÂPCT Int. Appl. WOÂ2016024286ÂA2Â20160218 (2016)
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