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產(chǎn)品基本信息

產(chǎn)品編號：B448525

產(chǎn)品名稱：Bisindolylmaleimide X Hydrochloride

產(chǎn)品CAS：145317-11-9

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標(biāo)準(zhǔn)品編號:	B448525
名稱:	Bisindolylmaleimide X Hydrochloride
別名:	3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Hydrochloride; 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Monohydrochloride;
CAS號:	145317-11-9
參考CAS:	Free Base: 131848-97-0
分子式:	C??H??ClN?O?
分子量:	460.96
類別:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Bisindolylmaleimide X hydrochloride is a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCα by Bisindolylmaleimide X and other similar PKC inhibitors has been associated with enhanced cardiac contractility and protection from heart failure.
文獻	Wilkinson, S.E. et al.: Biochem. J., 294, 335 (1993); Liu, Q., Chen, X. et al.: . Circ. Res. 105, 194 (2009); Birchall, A.M. et al.: J. Pharmacol. Exp. Ther., 268, 922 (1994);

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