Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
Labelled Chaetomellic acid B (C291830). It is an alkyl dicarboxylic acid isolated from the fermentation of Chaetomella acutiseta. Chaetomellic acid B has been shown to be a potent, highly specific inhibitor of RAS farnesyl protein transferase (FPTase). ÂThe association between RAS proteins and cancer has made Chaetomellic acid B a potential chemotherapeutic agent.
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