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               (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidi 
              
         		 
             
              
     
                
            
                
     
                 產(chǎn)品基本信息 
                
     
                
    
                 
                
     
                
     
                  產(chǎn)品編號(hào)：C377870  
                
     
                
     
                  產(chǎn)品名稱：(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidi  
                
     
                
     
                  產(chǎn)品CAS：1001264-89-6  
                
     
                
     
                  規(guī)格含量：10mg  
                
     
                
     
                  產(chǎn)品價(jià)格：面議  
                
     
                
     
                  
                  
     
                    
                    
     
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                  產(chǎn)品詳細(xì)介紹 
                 
     
                 
     
                  
                    
    
         
    
                        標(biāo)準(zhǔn)品編號(hào):
                        C377870
     
    
                        名稱:
                        (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone
     
    
                        別名:
                        GDC-0068; Ipatasertib; RG 7440;
     
    
                        CAS號(hào):
                        1001264-89-6
     
    
                        分子式:
                        C??H??ClN?O?
     
    
                        外觀:
                        Peach Solid
     
    
                        熔點(diǎn):
                        >106°C (dec.)
     
    
                        分子量:
                        458
     
    
                        儲(chǔ)存:
                        Hygroscopic, 冰箱保存, under inert atmosphere
     
    
                        溶解度:
                        Acetonitriele (Slightly), DMSO (Slightly), Methanol (Slightly)
     
    
                        類別:
                         Research Tools; Pharmaceutical/API Drug Impurities/Metabolites; 
     
    
                        應(yīng)用:
                        (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective AKT inhibitor targeting Akt1, Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.
      
    
    參考文獻(xiàn)
    
      
      
            
    

        
    
      
    
                      		
                 
     
                     
               
     
                  		 
             
    
                 
           
     
          
     
             		 
        
     
            
      
     
         		 
      
       
       
       
       
        
       
       
       
       
       
       
      
    
     
        
  
     
 
     

     
 
  
     
    
   
     
    

     
    
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     Keywords: 
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