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產(chǎn)品基本信息

產(chǎn)品編號：D288248

產(chǎn)品名稱：Desethyl Sacubitril-d4

產(chǎn)品CAS：

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	D288248
名稱:	Desethyl Sacubitril-d4
別名:	(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoic Acid-d4; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid-d4; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid-d4; LBQ 657-d4; Sacubitrilat-d4; [S-(R,S)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid-d4
參考CAS號:	類似: 149709-44-4
分子式:	C??H??D?NO?
外觀:	白色固體
熔點:	158-164°C
分子量:	387.46
儲存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
種類:	Standards; Isotopic Labeled Analogues;
應用:	Desethyl Sacubitril-d4 is the labelled, deuterated version of Desethyl Sacubitril which is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
參考文獻	McMurray, J., et al.: N. Eng. J. Med., 371 (2014);

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