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產(chǎn)品基本信息

產(chǎn)品編號(hào)：D462095

產(chǎn)品名稱：N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine

產(chǎn)品CAS：136768-57-5

規(guī)格含量：250mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	D462095
名稱:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine
別名:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethylenediamine; N,N'-Dimethyl-N,N'-bis(pyridin-2-ylmethyl)-1,2-diaminoethane; N1,N2-Dimethyl-N1,N2-bis(2-pyridinylmethyl)-1,2-ethanediamine; N,N'-Bis(2-pyridylmethyl)-N,N'-dimethyl-1,2-ethanediamine
CAS號(hào):	136768-57-5
分子式:	C??H??N?
分子量:	270.37
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine is an intermediate used in the synthesis of 8-Hydroxy Efavirenz (H941830), which is a metabolite of Efavirenz (E425000), a non-nucleoside HIV-1 reverse transcriptase inhibitor. Also, it is a potential candidates for bioreductively activated prodrug.
參考文獻(xiàn)	Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309(2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003); da Silva, A. F., et al.: Polyhedron, 123, 132-137 (2017)

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