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產品基本信息
產品編號:I809017
產品名稱:Ibufenac-13C6
產品CAS:
規(guī)格含量:5mg
產品價格:面議
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產品詳細介紹
標準品編號:
I809017
名稱:
Ibufenac-13C6
別名:
4-(2-Methylpropyl)benzeneacetic Acid-13C6; 4-(2-Methylpropyl)phenylacetic Acid-13C6; 4-Isobutoxyphenylacetic Acid-13C6; 4-Isobutylphenylacetic Acid-13C6; Dytransin-13C6; Ibunac-13C6; Medirex-13C6; NSC 99976-13C6
參考CAS號:
1553-60-2
分子式:
C?¹³C?H??O?
分子量:
198.21
溶解度:
Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
種類:
Standards; Isotopic Labeled Analogues;
應用:
Ibufenac-13C6 is an intermediate in synthesizing Ibuprofen-13C6 (I140003), a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
參考文獻
Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)