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產(chǎn)品基本信息

產(chǎn)品編號(hào)：B796595

產(chǎn)品名稱：tert-Butyl (3-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluorome

產(chǎn)品CAS：

規(guī)格含量：100mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	B796595
名稱:	tert-Butyl (3-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluoromethyl)phenyl)carbamate
分子式:	C??H??F?N?O?
外觀:	Beige Solid
分子量:	564.56
儲(chǔ)存:	Room Temperature
溶解度:	Dichloromethane; Methanol
類別:	Building Blocks; Miscellaneous;
應(yīng)用:	tert-Butyl (3-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluoromethyl)phenyl)carbamate is an intermediate for the synthesis of Nilotinib 3-Imidazolyl N-oxide (M326296), which is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia.
參考文獻(xiàn)	Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

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