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產(chǎn)品基本信息
產(chǎn)品編號：B810545
產(chǎn)品名稱：BX 471
產(chǎn)品CAS：217645-70-0
規(guī)格含量：5mg
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
B810545
名稱:
BX 471
別名:
(2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine; (2R)-1-[[[4-Chloro-2-(ureido)phenoxy]methyl]carbonyl]-2-methyl-4-(4-fluorobenzyl)piperazine; N-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]urea
CAS號:
217645-70-0
分子式:
C??H??ClFN?O?
分子量:
434.89
類別:
Standards; Enzyme Activators and Inhibitors;
應用:
BX 471 iS A C-C chemokine receptor 1(CCR1) antagonist. The CCR1 is implicated in diseases such as multiple myeloma, rheumatoid arthritis, and multiple sclerosis and therefore BX 471 may be used in treatment of such diseases.
參考文獻
Meritt, J., et al.: J. Med. Chem., 52, 1295 (2009); Choi, S., et al.: Chemokine-inhibiting piperazine derivatives and their use to treat multiple myeloma, WO Patent 2005077372, Aug 25, 2005;
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