產(chǎn)品基本信息
產(chǎn)品編號(hào)：E945410
產(chǎn)品名稱：seco Everolimus B
產(chǎn)品CAS：769905-89-7
規(guī)格含量：1mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
E945410
名稱:
seco Everolimus B
別名:
(2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoacetyl]-2-piperidinecarboxylic Acid
CAS號(hào):
769905-89-7
分子式:
C??H??NO??
外觀:
light Beige Solid
熔點(diǎn):
>110°C (dec.)
分子量:
976.24
儲(chǔ)存:
-20°C Freezer, Under inert atmosphere
溶解度:
Methanol (Slightly)
種類:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
seco Everolimus B is a metabolite of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.
參考文獻(xiàn)
Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)
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