Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
(R)-2-(2-((hydroxymethyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-N-methylacetamide is an adduct impurity of Pramipexole (P700750) formaldehyde. Pramipexole (P700750) is a dopamine-D2-receptor agonist. Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
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