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產(chǎn)品基本信息

產(chǎn)品編號(hào)：H949970

產(chǎn)品名稱：12-Hydroxy Nevirapine 12-O-β-D-Glucuronide

產(chǎn)品CAS：245500-95-2

規(guī)格含量：5mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	H949970
名稱:	12-Hydroxy Nevirapine 12-O-β-D-Glucuronide
別名:	(11-Cyclopropyl-6,11-dihydro-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-4-yl)methyl β-D-Glucopyranosiduronic Acid
CAS號(hào):	245500-95-2
分子式:	C??H??N?O?
分子量:	458.42
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	12-Hydroxy Nevirapine 12-O-β-D-Glucuronide is the O-glucuronide derivative of 12-Hydroxy Nevirapine (C988365); a metabolite of Nevirapine (N391275) which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Also antiviral.
參考文獻(xiàn)	Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999); Erickson, D.A., et al.: Drug Metab. Dispos., 27, 1488 (1999); Riska, P.S., et al.: Drug Metab. Dispos., 27, 1434 (1999)

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