Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
6-(2-Phenylethenyl)oxane-2,4-dione is an intermediate in the synthesis of rac-Kavain-d3 (K145492), which is the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
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