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產(chǎn)品基本信息

產(chǎn)品編號：S083602

產(chǎn)品名稱：SAG-d3

產(chǎn)品CAS：

規(guī)格含量：10mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	S083602
名稱:	SAG-d3
別名:	3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide-d3;
參考CAS號:	912545-86-9 unlabelled
分子式:	C??H??D?ClN?OS
分子量:	493.08
類別:	Building Blocks; Isotopic Labeled Analogues;
應(yīng)用:	SAG-d3 is the isotope labelled analog of SAG. SAG is a potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15.
參考文獻(xiàn)	DeCamp, D., et al.: J. Biol. Chem., 275, 26322 (2000), Ahn, S., et al.: Nature, 437, 894 (2005), Huangfu, D., et al.: Development, 133, 3 (2006), Loulier, K., et al.: J. Neurochem., 98, 530 (2006),

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