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產(chǎn)品基本信息

產(chǎn)品編號：C882945

產(chǎn)品名稱：3-Cyclobutoxy-4-(difluoromethoxy)benzaldehyde

產(chǎn)品CAS：290307-39-0

規(guī)格含量：50mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	C882945
名稱:	3-Cyclobutoxy-4-(difluoromethoxy)benzaldehyde
CAS號:	290307-39-0
分子式:	C??H??F?O?
外觀:	Colourless Oil
分子量:	242.22
儲存:	冰箱保存
溶解度:	Dichloromethane; Ethyl Acetate
類別:	Building Blocks; Miscellaneous;
應用:	3-Cyclobutoxy-4-(difluoromethoxy)benzaldehyde is an intermediate for the synthesis of O-Des(Cyclopropylmethyl) O-cyclobutyl Roflumilast (C982940), which is an intermediate used in the synthesis of Roflumilast (R639700). Roflumilast is a selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease.
參考文獻	Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al.: Lancet, 366, 563 (2005)

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