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產(chǎn)品基本信息

產(chǎn)品編號：A625980

產(chǎn)品名稱：N-(2-Aminophenyl)-N’-phenylheptanediamide

產(chǎn)品CAS：537034-15-4

規(guī)格含量：10mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	A625980
名稱:	N-(2-Aminophenyl)-N’-phenylheptanediamide
別名:	N1-(2-Aminophenyl)-N7-phenylheptanediamide;
CAS號:	537034-15-4
分子式:	C??H??N?O?
狀態(tài)：	灰白色至淺褐色固體
熔點(diǎn)：	155-157Â°C
分子量:	325.4
儲存：	-20Â°C Freezer
溶解性:	DMSO, Methanol
類別:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Histone deacetylase inhibitor IV. A cell-permeable pimeloylanilide compound that acts as a FXN-(frataxin gene) specific HDAC inhibitor. Reverses the silencing of FXN transcription in FRDA (Friedrichâ€™s ataxia) cells due to hypoacetylation of histones H3 and H4.
參考:	Dunah, A., et al.: Science, 296, 2238 (2002), Ferrante, R., et al.: J. Neurosci., 23, 9418 (2003), Gardian, G., et al.: J. Biol. Chem., 280, 556 (2005), Herman, D., et al.: Nat. Chem. Biol., 2, 551 (2006), Beckers, T., et al.: Int. J. Cancer, 121, 1138 (2007),

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