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產(chǎn)品基本信息

產(chǎn)品編號(hào)：C125420

產(chǎn)品名稱：Calcein AM (Mixture of Structural Isomers)

產(chǎn)品CAS：

規(guī)格含量：1mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	C125420
名稱:	Calcein AM (Mixture of Structural Isomers)
別名:	N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy)methyl] Ester; Calcein Acetoxymethyl Ester; NSC 689290;
參考CAS:	Component: 148504-34-1
分子式:	C??H??N?O??
分子量:	994.86
類別:	Research Tools; Molecular Biology; Fluorescent Reagents; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
參考文獻(xiàn)	Feller, N., et al.: Br. J. Cancer, 72, 543 (1995); Dhar, S., et al.: Eur. J. Pharmacol., 346, 315 (1998); Essodaigui, M., et al.: Biochemistry, 37, 2243 (1998); Lemasters, J.J., et al.: Biochim. Biophys. Acta., 1366,177 (1998);

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