cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI 906; OSI 906AA;
CAS號(hào):
867160-71-2
分子式:
C??H??N?O
外觀:
Pale Yellow to 淡黃色固體
熔點(diǎn):
>175°C (dec.)
分子量:
421.49
儲(chǔ)存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly, Heated)
種類:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent. Potent IGF-1R inhibitor.
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