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產(chǎn)品基本信息

產(chǎn)品編號(hào)：D288245

產(chǎn)品名稱：Desethyl Sacubitril

產(chǎn)品CAS：149709-44-4

規(guī)格含量：5mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	D288245
名稱:	Desethyl Sacubitril
別名:	[S-(R,S)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid; Sacubitrilat; LBQ 657
CAS號(hào):	149709-44-4
分子式:	C??H??NO?
外觀:	白色至白色固體
熔點(diǎn):	166-168°C
分子量:	383.44
儲(chǔ)存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
參考文獻(xiàn)	McMurray, J., et al.: N. Eng. J. Med., 371 (2014);

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