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產(chǎn)品基本信息

產(chǎn)品編號：D445245

產(chǎn)品名稱：(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]qui

產(chǎn)品CAS：848078-06-8

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	D445245
名稱:	(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-4,9-diyl bis(2-methylpropyl) Ester Carbonic Acid
別名:	(S)-4,11-Diethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-4,9-diyl Diisobutyl Dicarbonate
CAS號:	848078-06-8
分子式:	C??H??N?O?
外觀:	White Powder
分子量:	592.64
溶解性:	Acetone, Dichloromethane, Methanol
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-4,9-diyl bis(2-methylpropyl) Ester Carbonic Acid is an intermediate in the synthesis of 12-Hydroxy Irinotecan (Mixture of Diastereomers) (H943545). 12-Hydroxy Irinotecan is a metabolite of Irinotecan (I767500) found in human bile and urine.
參考文獻	Lokeic, F. et al.: Clin. Cancer Res., 2, 1943 (1996); Dodds, H.M. et al.: Anti-cancer Drug Des., 16, 239 (2001); Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987); Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)

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