產(chǎn)品基本信息
產(chǎn)品編號(hào)：D448735
產(chǎn)品名稱：1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride
產(chǎn)品CAS：781649-84-1
規(guī)格含量：500mg
產(chǎn)品價(jià)格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
D448735
名稱:
1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride
別名:
1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride; 1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Dihydrochloride; 1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one Dihydrochloride; 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine Dihydrochloride
CAS號(hào):
781649-84-1
參考CAS號(hào):
Free Base: 185961-99-3
分子式:
C??H??Cl?N?O
外觀:
Gray to Dark Gray Solid
熔點(diǎn):
>256°C (dec.)
分子量:
291.18
儲(chǔ)存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:
DMSO (Slightly), Methanol (Slightly)
種類:
Building Blocks; Miscellaneous;
應(yīng)用:
1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one is an intermediate used to prepare (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974) for use as a calcitonin gene-related peptide receptor antagonist treating migraine headaches.
參考文獻(xiàn)
Burgey, C., et al.: Org. Lett., 10, 3235 (2008);
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