產(chǎn)品基本信息
產(chǎn)品編號(hào)：H950690
產(chǎn)品名稱：N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)
產(chǎn)品CAS：
規(guī)格含量：2.5mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
H950690
名稱:
N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide
分子式:
C??H??F?N?O?
外觀:
白色至Pale Beige Solid
熔點(diǎn):
>250°C (dec.)
分子量:
424.29
儲(chǔ)存:
-20°C Freezer
溶解度:
Dichloromethane (Slightly), DMSO (Slightly)
種類:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.
參考文獻(xiàn)
Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)
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