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產(chǎn)品基本信息

產(chǎn)品編號：I399800

產(chǎn)品名稱：3β-17-Imino-androst-5-en-3-ol Dimer

產(chǎn)品CAS：491873-45-1

規(guī)格含量：500mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	I399800
名稱:	3β-17-Imino-androst-5-en-3-ol Dimer
CAS號:	491873-45-1
分子式:	C??H??N?O?
外觀:	白色至白色固體
熔點:	>251°C (dec.)
分子量:	572.86
儲存:	-20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly, Heated)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
應(yīng)用:	3β-17-Imino-androst-5-en-3-ol Dimer is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17). Abiraterone is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
參考文獻	Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

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