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產(chǎn)品基本信息

產(chǎn)品編號(hào)：O847255

產(chǎn)品名稱：3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic Acid Chloride

產(chǎn)品CAS：183020-20-4

規(guī)格含量：1g

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	O847255
名稱:	3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic Acid Chloride
別名:	3-Oxo-4-aza-5α-androst-1-ene-17β-carboxoyl Chloride; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carbonyl Chloride; (5α,17β)-3-Oxo-4-azaandrost-1-ene-17-carbonyl Chloride;
CAS號(hào):	183020-20-4
分子式:	C??H??ClNO?
分子量:	335.87
類別:	Standards; Steroids;
應(yīng)用:	3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic Acid Chloride is an intermediate used in the synthesis of Dutasteride β-Dimer (D735020), which is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.
參考文獻(xiàn)	Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)

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