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產(chǎn)品基本信息

產(chǎn)品編號：O869500

產(chǎn)品名稱：3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid

產(chǎn)品CAS：103335-55-3

規(guī)格含量：10g

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	O869500
名稱:	3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid
別名:	3-Oxo-4-aza-5α-androstane-17-carboxylic Acid; 3-Oxo-4-aza-5α-androstane-17β-carboxylic Acid; 4-Aza-3-oxo-5α-androstane-17β-carboxylic Acid; 4-Aza-3-oxo-androstane-17β-carboxylic Acid; (5α,17β)-3-Oxo-4-azaandrostane-17-carboxylic Acid; (5α,17β)-3-Oxo-4-aza-5α-androstane-17-carboxylic Acid; (5α,17β)-3-Oxo-4-azaandrostane-17-carboxylic Acid; [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]Hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid
CAS號:	103335-55-3
分子式:	C??H??NO?
外觀:	白色至白色固體
熔點:	>300°C (dec.)
分子量:	319.44
儲存:	冰箱
溶解度:	DMSO (Sparingly), Methanol (Very Slightly, Heated, Soniciated)
類別:	Standards; Steroids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid is an impurity in the synthetic process of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
參考文獻	Zhang, K. et al.: J. Chin. Pharm. Sci., 16, 233 (2007); Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),

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