Standards; Nucleic Acids; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
應(yīng)用:
1-[4-Azido-3-O-benzoyl-5-O-(3-chlorobenzoyl)-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil is reported to be a reactant used for the preparation of 2'-deoxy-2'-fluoro-4'-azido nucleoside analogs which exhibited extremely potent anti-HIV activity against NL4-3 (wild-type), NL4-3 (K101E), and RTMDR viral strains. Also it is used for the synthesis of 4-substituted fluoronucleoside analogs for the treatment of Hepatitis B virus infection.
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