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產(chǎn)品基本信息

產(chǎn)品編號(hào)：D451538

產(chǎn)品名稱：1,1-Difluoro-4-(iodomethyl)cyclohexane

產(chǎn)品CAS：476415-02-8

規(guī)格含量：250mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	D451538
名稱:	1,1-Difluoro-4-(iodomethyl)cyclohexane
CAS號(hào):	476415-02-8
分子式:	C?H??F?I
分子量:	260.06
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
應(yīng)用:	1,1-Difluoro-4-(iodomethyl)cyclohexane is derived from 4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester (D445698), which is used as a reactant in the preparation of antiretroviral drug Maraviroc (M193000), which is CCR-5 receptor antagonist used for treatment of HIV.
參考文獻(xiàn)	Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003); Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005); Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005); Haycock-Lewandowski, S., et al.: Org. Process Res. Dev., 12, 1094 (2008);

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