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產(chǎn)品基本信息

產(chǎn)品編號：R701525

產(chǎn)品名稱：Ruboxistaurin Hydrochloride

產(chǎn)品CAS：169939-93-9

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	R701525
名稱:	Ruboxistaurin Hydrochloride
別名:	(9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride; LY 333531 Hydrochloride;
CAS號:	169939-93-9
參考CAS號:	Free Base: 169939-94-0
分子式:	C??H??ClN?O?
分子量:	505.01
類別:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications.
參考文獻	Miller, J., et al.: Diabetes Metab. Rev., 13, 37 (1997), Suzuma, I., et al.: J. Biol. Chem., 277, 1047 (2002), Ali, N., et al.: J. Pharmacol. Sci., 98, 130 (2005),

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