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產(chǎn)品基本信息

產(chǎn)品編號：C380745

產(chǎn)品名稱：N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-

產(chǎn)品CAS：1255529-28-2

規(guī)格含量：25mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	C380745
名稱:	N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide
別名:	Edoxaban Impurity H; 2,4-diepi-Edoxaban; (2S,4R)-Edoxaban;
CAS號:	1255529-28-2
分子式:	C??H??ClN?O?S
分子量:	548.06
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide or Edoxaban Impurity H is an impurity of Edoxaban (E555520) which is an anticoagulant drug which acts as a direct factor Xa inhibitor. Edoxaban Impurity H serves as a useful pharmaceutical standard.
參考文獻(xiàn)	Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010); Yoshino, T., et al.: Preparation of stereoisomers of N1-(5-chloropyridin-2-yl)-N2-[(1S, 2R, 4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide as pharmaceutical standards and as drugs for treating thrombosis, US Patent 20120053349, Mar 1, 2012;

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