(2R,?3E)?-2,?4-?Dimethyl-?2-?[(1-?oxopropyl)?thio]?-?3,?5-?hexadienoic Acid Ethyl Ester is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).