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產(chǎn)品基本信息

產(chǎn)品編號：I814125

產(chǎn)品名稱：Isodemecolcine

產(chǎn)品CAS：4702-33-4

規(guī)格含量：100mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	I814125
名稱:	Isodemecolcine
別名:	(S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)-benzo[a]heptalen-10(5H)-one; Isocolchicine;
CAS號:	4702-33-4
分子式:	C??H??NO?
分子量:	371.43
種類:	Standards; Enzyme Activators and Inhibitors;
應(yīng)用:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
參考文獻(xiàn)	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),

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