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產(chǎn)品基本信息

產(chǎn)品編號：L320105

產(chǎn)品名稱：Ledipasvir Impurity A

產(chǎn)品CAS：

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	L320105
名稱:	Ledipasvir Impurity A
別名:	Methyl ((R)-1-((1R,3S,4S)-3-(6-(9,9-difluoro-7-(2-((S)-5-((R)-3-methyl-2-((methylcarbamoyl)oxy)butanoyl)-5-azaspiro[2.4]heptan-6-yl)-1H-imidazol-5-yl)-9H-fluoren-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptan-2-yl)-3-methyl-1-oxobutan-2-yl)carbamate; Methyl [(2R)-1-{(6S)-6-[5-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2R)-2-[(methoxy carbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-6-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1-oxobutan-2-yl]carbamate
參考CAS號:	1256388-51-8
分子式:	C??H??F?N?O?
分子量:	889
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Ledipasvir Impurity A is an impurity of Ledipasvir, which is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.
參考文獻	Lawitz, E., et al.: J. Hepatol., 57, 24 (2012); Afdhal, N., et al.: New England J. Med., 370, 1889 (2014)

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