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產(chǎn)品基本信息

產(chǎn)品編號：M687545

產(chǎn)品名稱：Carfilzomib (2R,4S)-2-Hydroxy Acetate

產(chǎn)品CAS：1541171-69-0

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	M687545
名稱:	Carfilzomib (2R,4S)-2-Hydroxy Acetate
別名:	(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3R)-4-(acetyloxy)-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide
CAS號:	1541171-69-0
分子式:	C??H??N?O?
外觀:	白色固體
分子量:	779.96
儲存:	-20°C Freezer
溶解度:	Chloroform; Methanol; Acetonitrile; DMSO
種類:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Carfilzomib (2R,4S)-2-Hydroxy Acetate is an intermediate for the synthesis of Carfilzomib (2R,4S)-Diol (C183470), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
參考文獻	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);

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