對照品 > 標(biāo)準(zhǔn)品 > 歐洲藥典標(biāo)準(zhǔn)品 >
產(chǎn)品基本信息
產(chǎn)品編號：N515875
產(chǎn)品名稱：2-(4-Nitro-1,3-dioxoisoindolin-2-yl)pentanedioic Acid
產(chǎn)品CAS：18636-08-3
規(guī)格含量：50mg
產(chǎn)品價格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
N515875
名稱:
2-(4-Nitro-1,3-dioxoisoindolin-2-yl)pentanedioic Acid
別名:
2-(1,3-Dihydro-4-nitro-1,3-dioxo-2H-isoindol-2-yl)pentanedioic Acid; 1-(4-Nitro-1,3-dioxoisoindolin-2-yl)propane-1,3-dicarboxylic Acid
CAS號:
18636-08-3
分子式:
C??H??N?O?
外觀:
Yellow Solid
分子量:
322.23
溶解度:
DMF; Methanol
種類:
Building Blocks; Miscellaneous;
應(yīng)用:
2-(4-Nitro-1,3-dioxoisoindolin-2-yl)pentanedioic Acid is an intermediate in the synthesis of Pomalidomide (P688200), a thalidomide derivative and a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
參考文獻(xiàn)
Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)
?您的位置：
