Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Isotope Labelled analogue of Tariquidar (T007600), a p-glycoprotein drug efflux pump inhibitor. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both.Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer
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