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產(chǎn)品基本信息

產(chǎn)品編號：B330240

產(chǎn)品名稱：Betulin

產(chǎn)品CAS：473-98-3

規(guī)格含量：5g

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	B330240
名稱:	Betulin
別名:	Lup-20(29)-ene-3Î²,28-diol; Lup-20(30)-ene-3Î²,28-diol; 3aH-Cyclopenta[a]chrysene, lup-20(29)-ene-3,28-diol deriv.; (+)-Betulin; 3,28-Dihydroxy-lupeol; 3Î²,28-Dihydroxylup-20(29)-ene; Betulin; Betuline; Betulinic alcohol; Betulinol; Betulol; NSC 4644; Trochol
CAS號:	473-98-3
分子式:	C??H??O?
外觀：	Pale Brown to Beige Solid
熔點(diǎn):	>250Â°C (dec.)
分子量:	442.72
儲存:	Hygroscopic, -20Â°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly, Heated)
穩(wěn)定性:	Hygroscopic
類別:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Betulin is a derivative of Betulinic Acid (B330250), used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
文獻(xiàn)	Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010);

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