產(chǎn)品名稱：Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
產(chǎn)品CAS：
規(guī)格含量：10g
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
I824640
名稱:
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
別名:
N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2-((Hydroxy(phenoxy)phosphoryl)amino)propanoate Sodium Salt
參考CAS號:
free acid: 1520010-86-9
分子式:
C??H??NNaO?P
分子量:
309.23
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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