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產品基本信息

產品編號：M326296

產品名稱：Nilotinib 3-Imidazolyl N-oxide

產品CAS：2139382-75-3

規(guī)格含量：25mg

產品價格：面議

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產品詳細介紹

標準品編號:	M326296
名稱:	Nilotinib 3-Imidazolyl N-oxide
別名:	Nilotinib Impurity; 4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine
CAS號:	2139382-75-3
分子式:	C??H??F?N?O?
外觀:	淡黃色固體
熔點:	>156°C (dec.)
分子量:	545.52
儲存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly, Heated)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia.
參考文獻	Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

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